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Antex Biologics has developed VEP (Virulence Expression Profiling) platform, a new genomics-based platform technology that reveals the blueprint of infectious bacteria in their host environment. VEP can duplicate in the laboratory the way bacteria grows in the human body and identify the disease-causing proteins of a bacteria at the genomic level. Cell Genesys and the National Institutes of Health announced that in non-human primate models of hemophilia B, therapeutic levels of factor IX were restored following a single administration of hemophilia gene therapy. The therapy, which was delivered to the liver using the company's proprietary adeno-associated viral gene delivery system, was shown to be safe and well-tolerated in a variety of clinical assays. In addition, an immune response against the gene therapy, as measured by the development of anti-factor IX antibodies, was not observed. ChromaVision Medical Systems, Inc. has introduced the new ACIS DNA Ploidy test to be run on the Automated Cellular Imaging System (ACIS). The test measures the DNA content within the nuclei of cancer cells, as a prognostic indicator in multiple cancer types. DNA Ploidy tests are a component of the primary panel of tests performed to characterize cancer tumors and determine the aggressiveness of those tumors. Specialty Laboratories will be using SEQUENOM's MassARRAY system to perform genetic analyses to detect variations, or single nucleotide polymorphisms (SNPs), that are associated with specific diseases. In doing so, Specialty becomes the first U.S. diagnostics reference laboratory to use mass spectrometry for clinical diagnostics testing.
Molecular Biology - May 2000
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