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Biosite Diagnostics Inc. and Large Scale Biology Corp. are collaborating to generate the antibody and protein target components required to produce the first generation of commercial protein arrays for clinical research, diagnostics and toxicology. Large Scale's proteomics unit expects to provide 2000 - 5000 protein targets from its human protein index, Biosite will use its Omniclonal phage display technology to generate antibodies to the targets.

Scientists at the University of Wisconsin have decoded the DNA of E. coli type O157:H7. The researchers discovered that the E. coli strain picks up swatches of genetic material from other bacteria and viruses. The group had already mapped a non-virulent version of E. coli. They found that the virulent strain of E. coli shares about 3,500 genes with the non-virulent species, but the E. coli O157:H7 strain has about 1,300 additional genes.
Source: Nature, January 2001.

Cryoma Labs has launched a tumor cell bank and will freeze and store tumor cells for the future benefit of cancer patients. Cryoma will work closely with oncologists, surgeons and cancer patients to provide storage of patient-donated tumor tissue samples designed for the development of personalized cancer vaccines.

Ventana Medical Systems Inc. will integrate Genicon Sciences Corp.'s RLS Technology into Ventana's Discovery instrument for automated microarrays and signal generation. The companies plan to launch a Genicon RLS Tech toolkit on the Discovery in late 2001. The collaboration extends to ISH and IHC staining of tissue.

Biopool subsidiary XTRANA and Beckman Coulter have entered into a collaborative agreement to make DNA extraction kits available on Beckman Coulter's laboratory automation systems. The kits will be available from Beckman Coulter in 2001 and will process whole blood for life science research. The five-year agreement gives Beckman Coulter non-exclusive, worldwide rights to distribute XTRANA's proprietary Xtra Amp nucleic acid extraction kits for use with the company's laboratory automation systems, including the Biomek brand laboratory automation workstations.

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