The following is a review of diagnostics related medical research worldwideThe information is updated the first week of every month - so ... make this a regular stop in your information gathering activities.The following information has been compiled from publicly available sources, StratCom does not assume any responsibility for the accuracy or the authenticity of the information and StratCom cannot be held liable for errors.
Research News for December 2001Researchers associated with AstraZeneca, Mölndal, Sweden, and the Apolipoprotein-related Mortality Risk Study have found that high levels of apolipoprotein B (apoB) and low levels of apolipoprotein A-I (apoA-I) are highly predictive of fatal myocardial infarction, regardless of lipid concentrations. The researchers suggest that although LDL-cholesterol and HDL-cholesterol are known risk factors, apoB, apoB/apoA-I, and apoA-I should also be regarded as highly predictive in evaluation of cardiac risk. However, before apoB and apoA-I can be used in routine clinical practice, assay methods need to be standardised and threshold and target values for diagnosis and treatment need to be agreed. Dr. Klaus A. Dugi from the University of Heidelberg in Germany has found that low levels of hepatic lipase, a liver enzyme that helps metabolize HDL cholesterol may be an independent risk factor for coronary artery disease. His research shows that some people with a genetic deficiency in hepatic lipase develop premature artery disease. The extent of artery narrowing and hardening increased as hepatic lipase activity decreased, regardless of factors like age, body mass and high blood pressure.
Research News - November 2001
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