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Researchers at the University of Pennsylvania are researching the presence of isoprostanes, fatty acids that are associated with oxidative damage in the brain in urine. It is thought that their findings may one day lead to a urine test to identify people who are at an increased risk of developing Alzheimer's. Oxidative damage is caused by free radicals, which are cell-damaging byproducts of the body's natural metabolic processes, and has been implicated in heart disease and cancer. Some researchers also believe oxidative damage may play a role in the development of Alzheimer's.
Source: Archives of Neurology June 2002;59:972-976.