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The following information has been compiled from publicly available sources, StratCom does not assume any responsibility for the accuracy or the authenticity of the information and StratCom cannot be held liable for errors.

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Molecular Biology — December 2002

Amnis, has received a SBIR Phase II grant of $750,000 from the National Cancer Institute (NCI), a component of the National Institutes of Health (NIH) to develop velocity detection and autofocus technology for a commercial version of the company's ImageStream technology for imaging cells in flow.

Beckman Coulter, Inc. has acquired rights to the SNP genotyping instrumentation, reagents and software formerly marketed by Orchid Life Sciences, and received an exclusive license to use Orchid's SNP-IT SNP analysis technology in products sold to the research and specialty testing markets. In addition, Beckman Coulter was granted a non-exclusive license to use SNP-IT in the field of diagnostics.

BioForce Nanosciences, Inc. has received a Department of Defense grant for breast cancer research to construct a nano-scale protein array platform and use it as a basic research tool to study alterations in cellular signaling pathways that accompany breast cancer disease progression.

Cepheid has introduced its next generation real-time DNA analysis system, the Smart Cycler II. The multiplexed optical detection system has been enhanced to give users more flexibility and more choice in the use of next generation fluorescent detection dyes, chemistries, and techniques.

ILEX Oncology Inc. has signed a sublicensing agreement with Ventana Medical Systems for its CAMPATH-related diagnostic testing. Ventana received exclusive worldwide diagnostic rights to develop and commercialize an immunohistochemistry test to detect the presence of the CD52 antigen in lymph nodes and potentially in certain solid tumors.

Nanogen, Inc. has signed a non-exclusive license agreement with Athena Diagnostics that grants Nanogen a worldwide, non-exclusive license to certain patents and patent applications relating to methods of using Apolipoprotein E (ApoE) isoforms, or any nucleic acid sequence relating to a gene encoding such isoforms, associated with the detection, diagnosis and monitoring of Alzheimer's disease.

Vysis, Inc. has introduced its Breast Aneusomy Probe Set for breast cancer research for FISH detection of gains or losses of chromosome 1, 8, 11, and 17.

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