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Dear Reader, it is time for our annual summer hiatus - time for BBQ, sun and beach. Have a great summer. We will be back in September. Agilent Technologies Inc. has introduced microfluidics-based technology for liquid chromatography/mass spectrometry (LC/MS), used in protein research and pharmaceutical applications to separate and identify biological compounds. The centerpiece of the new technology is a reusable polymer high-performance LC (HPLC) chip that eliminates the need for traditional LC columns. BD Diagnostics has received FDA clearance to market for the BD ProbeTec ET Legionella pneumophila DNA Amplified Assay. BTG has acquired a cellular fetal DNA diagnostic, developed by Professor Maj Hulten, that has the ability to identify fetal DNA from the mixed cell population in the maternal bloodstream. This will allow fetal chromosomes to be investigated for several chromosome disorders, including Trisomy 21 (underlying cause of Down syndrome) from a maternal blood sample, without contamination by maternal chromosomes. Telomere Depletion Assay (TDA), is based on the difference in telomere length between fetal and adult cells where fetal chromosomes are known to have longer repeats of the telomeric DNA sequence. Genaissance Pharmaceuticals, Inc. introduced the FAMILION Test, a genetic test for cardiac channelopathies. Cardiac channelopathies is a broad clinical category that includes Long QT and Brugada Syndromes, two causes of arrhythmia that can result in sudden cardiac death. The test is provided by Gennaissance's CLIA lab in New Haven, CT. LabCorp now offers a buccal swab test for alpha1-antitrypsin (AAT) deficiency, the most common, modifiable genetic factor leading to chronic obstructive pulmonary disease. In its severest forms, AAT deficiency can result in life-threatening lung or liver disease.
Molecular Biology - April 2004
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