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The following information has been compiled from publicly available sources, StratCom does not assume any responsibility for the accuracy or the authenticity of the information and StratCom cannot be held liable for errors.

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Molecular Biology — October 2004

Abbott and BioGenex Laboratories are collaborating to develop a system that will fully automate molecular diagnostic tests that employ Abbott/Vysis' FISH technology including the application, removal and re-application of the coverslip resulting in a completely finished slide that is ready to go directly on the microscope for review. It is expected to be introduced to the market in the near future, pending regulatory clearance.

Fuji Photo Film Co., Ltd. has introduced the QuickGene-800, a compact, tabletop DNA/RNA isolation system that can deliver a DNA whole blood sample in as little as 6 minutes. Operation is simple and convenient, allowing the operator to simply select a mode then press the start button. The system uses the FUJIFILM patented porous membrane, which binds nucleic acids and eliminates the need for a centrifuge. Kits for DNA in whole blood, DNA in tissue and RNA in cultured cells are now available. Other kits are in development.

GeneOhm Sciences, Inc. and Infectio Diagnostic announced their plans to merge. IDI has two FDA and Health Canada-cleared assays for Group B Streptococcus colonization in pregnant women at time of delivery and direct detection of MRSA. GSI has developed its proprietary platform, ePlex for multiplexed electrochemical detection of nucleic acids and propriety methods of sample processing. IDI will continue to supply its proprietary assays on the Cepheid Smart Cycler platform.

Gen-Probe has signed non-exclusive licensing agreements with bioMerieux and its affiliates that provide bioMerieux options to access Gen-Probe's ribosomal RNA technologies for certain uses, and that give Gen-Probe access to bioMerieux's intellectual property for detecting genetic mutations that predispose people to blood clotting disorders.

Nanogen, Inc. introduced its second-generation instrument, the NanoChip 400, an automated multi-purpose system for single nucleotide polymorphisms (SNPs), using a 400-site electronic microarray upon which molecular tests can be developed and conducted.

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