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The following information has been compiled from publicly available sources, StratCom does not assume any responsibility for the accuracy or the authenticity of the information and StratCom cannot be held liable for errors.

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Molecular Biology — December 2005

Applied Biosystems is buying the research products division of Ambion Inc. for about $273 million.

Gen-Probe Incorporated received FDA clearance to market the PROCLEIX West Nile virus assay to screen donated human blood on the PROCLEIX enhanced semi-automated instrument system (eSAS).

Gentra Systems Inc. introduced a new versaGene DNA Cell Purification Kit. The kit uses novel chemistry and column design to purify DNA that is virtually devoid of RNA and protein contamination.

Hitachi, Ltd. and Takara Bio have developed compact automatic virus detection system. The system uses Hitachi's proprietary virus collection system and virus genes analyzer and Takara Bio's ICAN (Isothermal and Chimeric P- rimer-Initiated Amplification of Nucleic Acids) method.

Quest Diagnostics developed a gene- based assay to help physicians identify metastatic Cancers of Unknown Primary origin (CUP) based on intellectual property licensed from Arcturus BioScience, Inc. The CUP assay is intended to aid the physician in identifying the primary site of origin of Cancers of Unknown Primary for 39 tumor types, establishing prognosis, and determining appropriate therapy.

Stratagene Corporation granted Focus Diagnostics a non-exclusive license to its proprietary FullVelocity technology, and will provide expertise and knowledge that Focus will use to develop selected molecular diagnostics testing kits and products. Stratagene will also manufacture the diagnostic products which Focus intends to commercialize globally. Stratagene will also manufacture and sell reagents to Focus for laboratory-developed tests to be used in Focus' national reference laboratory.

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